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Matrix gla protein
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・ Matrix metallopeptidase 13
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Matrix gla protein : ウィキペディア英語版
Matrix gla protein

Matrix gla protein (MGP) is member of a family of vitamin-K dependant, Gla-containing proteins. MGP has a high affinity binding to calcium ions, similar to other Gla-containing proteins. The protein acts as an inhibitor of vascular mineralization and plays a role in bone organization.
MGP is found in number body tissues in mammals, birds, and fish. Its mRNA is present in bone, cartilage, heart, and kidney.
It is present in bone together with the related vitamin K-dependent protein osteocalcin. In bone, its production is increased by vitamin D.
== Genetics ==
The ''MGP'' was linked to the short arm of chromosome 12 in 1990. Its mRNA sequence length is 585 bases long in humans.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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